Pathophysiology of hiv pdf

 

 

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PATHOPHYSIOLOGY OF HIV. AND VIRAL HEPATITIS. Roger Paredes, MD, PhD. Infectious Diseases Unit & irsiCaixa AIDS Research Intitute. CD4 T-cell depletion and chronic inflammation are the two signature events that drive HIV pathogenesis and progression to AIDS. · Infection of the cells of the HIV is a sexually transmitted disease. Infection is aided by Langerhans cells in mucosal epithelial surfaces which can become infected. Infection is also aided HIV attaches to and penetrates host T cells, then releases HIV RNA and enzymes into the host cell. HIV reverse transcriptase copies viral RNA as proviral DNA.

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